Articles Tagged With:
-
Rituximab Treatment for AChR Myasthenia Gravis: Results of the BeatMG Study
The B-Cell Targeted Treatment In Myasthenia Gravis (BeatMG) study was the first prospective, randomized, double-blind, placebo-controlled clinical trial to explore the role of targeted B-cell depletion in myasthenia patients. Although rituximab was found to be safe and well-tolerated, rituximab treatment did not confer a significant steroid-sparing effect compared to placebo. Results of a futility analysis suggested rituximab treatment would be unlikely to show a clinically meaningful improvement of 30% over placebo in a larger Phase III trial of mild to moderately symptomatic acetylcholine receptor autoantibody-positive generalized myasthenia gravis patients.
-
Plasma Biomarkers for Neurodegenerative Dementias: We Are Getting Closer
Two recent multicenter studies suggest that plasma biomarkers, including phosphorylated-tau181, could be used as cost-effective and more readily accessible biomarkers for the diagnosis and management of individuals with neurodegenerative dementias.
-
How Many Leads Are Abnormal?
The figure was obtained after cardiac catheterization for new chest pain. The rhythm is sinus bradycardia at ~50 beats/minute. All intervals are normal. The axis is leftward, but not enough to qualify as a hemiblock. There is no chamber enlargement.
-
Abrocitinib Tablets/Upadacitinib Extended-Release Tablets (Cibinqo/Rinvoq)
Abrocitinib and upadacitinib can be prescribed to treat adults with refractory, moderate-to-severe atopic dermatitis that is not adequately controlled with other systemic drug products, including biologics, or when using those therapies is inadvisable.
-
Booster Doses Effective Against Omicron
While vaccination provides protection against infection with omicron variant of SARS-CoV-2, high level protection from a need for hospitalization requires a booster dose.
-
Patients’ Goals During Long-Term Acute Care Hospital Stays
After a long-term acute care hospital stay, most patients will achieve goals of ventilator liberation, eating, drinking, and speaking, but many will not achieve independence in walking, grooming, toileting, or returning home.
-
Coffee and Tea: Drink Choice and Effects on Stroke, Dementia, and Poststroke Dementia
Moderate amounts of coffee and/or tea consumption were associated with the lowest hazard ratio of stroke and dementia, while coffee alone or in combination with tea was associated with a lower risk of poststroke dementia.
-
Association Between Breastfeeding and Blood Pressure at 3 Years of Age
Any breastfeeding, including within the first days of life, was associated with significantly lower systolic blood pressure at age 3 years in participants from the Canadian Healthy Infant Longitudinal Development Cohort Study.
-
Coffee and Tea: Drink Choice and Effects on Stroke, Dementia, and Poststroke Dementia
A long-term, large-scale prospective study revealed moderate amounts of coffee and/or tea consumption was associated with the lowest hazard ratio of stroke and dementia, while coffee alone or in combination with tea was associated with a lower risk of poststroke dementia.
-
More U.S. Trauma Centers Offering Screening, Intervention Programs
Integrated mental health approach includes addressing PTSD, alcohol, opioids, firearms, and suicidal ideation.